Short-Term Transcriptomic Points of Departure Are Consistent with Chronic Points of Departure for Three Organophosphate Pesticides across Mouse and Fathead Minnow

Short-Term Transcriptomic Points of Departure Are Consistent with Chronic Points of Departure for Three Organophosphate Pesticides across Mouse and Fathead Minnow

New approach methods (NAMs) can reduce the need for chronic animal studies. Here, we apply benchmark dose (concentration) (BMD(C))–response modeling to transcriptomic changes in the liver of mice and in fathead minnow larvae after short-term exposures (7 days and 1 day, respectively) to several dose...

书目详细资料
Main Authors:	Rubia Martin, Monique Hazemi, Kevin Flynn, Daniel Villeneuve, Leah Wehmas
格式:	文件
语言:	English
出版:	MDPI AG 2023-09-01
丛编:	Toxics
主题:	benchmark dose fathead minnow mouse organophosphate pesticides transcriptional points of departure
在线阅读:	https://www.mdpi.com/2305-6304/11/10/820

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