Kinetics of the Cell Cycle Arrest Biomarkers (TIMP2 and IGFBP7) for the Diagnosis of Acute Kidney Injury in Critically Ill COVID-19 Patients

Background: Acute kidney injury (AKI) is highly prevalent in critical COVID-19 patients. The diagnosis and staging of AKI are based on serum creatinine (sCr) and urinary output criteria, with limitations in the functional markers. New cell-cycle arrest biomarkers [TIMP2]*[IGFBP7] have been proposed...

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Main Authors: Massimiliano Greco, Silvia De Rosa, Fabian Boehm, Sofia Spano, Romina Aceto, Antonio Voza, Francesco Reggiani, Marta Calatroni, Gianluca Castellani, Elena Costantini, Gianluca Villa, Maurizio Cecconi
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/13/2/317