Nanotechnology for microglial targeting and inhibition of neuroinflammation underlying Alzheimer’s pathology

Nanotechnology for microglial targeting and inhibition of neuroinflammation underlying Alzheimer’s pathology

Abstract Background Alzheimer's disease (AD) is considered to have a multifactorial etiology. The hallmark of AD is progressive neurodegeneration, which is characterized by the deepening loss of memory and a high mortality rate in the elderly. The neurodegeneration in AD is believed to be exace...

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Bibliographic Details
Main Authors: Hoda M. Gebril, Aravind Aryasomayajula, Mariana Reis Nogueira de Lima, Kathryn E. Uhrich, Prabhas V. Moghe
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Translational Neurodegeneration
Subjects:
Amphiphilic nanoparticle
Microglia
Fibril amyloid beta
Alzheimer’s disease
Neuroinflammation
Scavenger receptor
Online Access:https://doi.org/10.1186/s40035-023-00393-7

Internet

https://doi.org/10.1186/s40035-023-00393-7

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