The 8q24 gene desert: an oasis of transcriptional activity

Understanding the functional effects of the wide-range of aberrant genetic characteristics associated with the human chromosome 8q24 region in cancer remains daunting due to the complexity of the locus. The most logical target for study remains the MYC protooncogene, a prominent resident of 8q24 th...

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Bibliographic Details
Main Authors: Konrad eHuppi, Jason J Pitt, Brady M Wahlberg, Natasha J Caplen
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00069/full