Snx27 Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation

Snx27 Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation

Sorting nexin 27 (SNX27) is an endosome-associated cargo adaptor that is involved in various pathologies and development of neurological diseases. However, the role of SNX27 in spinal cord injury (SCI) remains unclear. In this study, we found that SNX27 was up-regulated in injured mice spinal cords...

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Bibliographic Details
Main Authors: Yuzhe Zeng, Nawen Wang, Tiantian Guo, Qiuyang Zheng, Shuang Wang, Songsong Wu, Xi Li, Jin Wu, Zhida Chen, Huaxi Xu, Xin Wang, Bin Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Neurology
Subjects:
sorting nexin 27
neuroprotection
macrophage/microglia
functional recovery
spinal cord injury
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.01059/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.01059/full

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