Creatine Acts as a Mediator of the Causal Effect of Obesity on Puberty Onset in Girls: Evidence from Mediation Mendelian Randomization Study

Epidemiological studies have linked obesity to the onset of puberty, while its causality and the potential metabolite mediators remain unclear. We employed a two-sample Mendelian randomization (MR) design to evaluate the causal effects of obesity on puberty onset and its associated diseases includin...

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Bibliographic Details
Main Authors: Chuandi Jin, Guoping Zhao
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/14/3/137