MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies
Oncogene addiction is considered as a cancer cell-autonomous phenomenon, but can also influence the host immune system. Here the authors show that MYC-driven lymphomagenesis is associated with a block in the maturation and effector functions of natural killer cells as a mechanism of tumor escape fro...
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Bibliographic Details
| Main Authors: |
Srividya Swaminathan,
Aida S. Hansen,
Line D. Heftdal,
Renumathy Dhanasekaran,
Anja Deutzmann,
Wadie D. M. Fernandez,
Daniel F. Liefwalker,
Crista Horton,
Adriane Mosley,
Mariola Liebersbach,
Holden T. Maecker,
Dean W. Felsher |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2020-06-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-16447-7
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