Lack of complex type N-glycans lessens aberrant neuronal properties.

Modifications in surface glycans attached to proteins via N-acetylglucosamine-β1-N-asparagine linkage have been linked to tumor development and progression. These modifications include complex N-glycans with high levels of branching, fucose and sialic acid residues. Previously, we silenced Mgat2 in...

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Bibliographic Details
Main Authors: M Kristen Hall, Douglas A Weidner, Austin A Whitman, Ruth A Schwalbe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6002081?pdf=render