Differential thermal stability and oxidative vulnerability of the hemoglobin variants, HbA2 and HbE.

Apart from few early biophysical studies, the relative thermal instability of HbE has been only shown by clinical investigations. We have compared in vitro thermal stability of HbE with HbA2 and HbA using optical spectroscopy. From absorption measurements in the soret region, synchronous fluorescenc...

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Bibliographic Details
Main Authors: Abhijit Chakrabarti, Dipankar Bhattacharya, Sanghamitra Deb, Madhumita Chakraborty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3828284?pdf=render