Mouse mammary tumor virus is implicated in severity of colitis and dysbiosis in the IL-10−/− mouse model of inflammatory bowel disease

Mouse mammary tumor virus is implicated in severity of colitis and dysbiosis in the IL-10−/− mouse model of inflammatory bowel disease

Abstract Background Following viral infection, genetically manipulated mice lacking immunoregulatory function may develop colitis and dysbiosis in a strain-specific fashion that serves as a model for inflammatory bowel disease (IBD). We found that one such model of spontaneous colitis, the interleuk...

Full description

Bibliographic Details
Main Authors: Heather Armstrong, Mandana Rahbari, Heekuk Park, David Sharon, Aducio Thiesen, Naomi Hotte, Ning Sun, Hussain Syed, Hiatem Abofayed, Weiwei Wang, Karen Madsen, Eytan Wine, Andrew Mason
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Microbiome
Subjects:
Inflammatory bowel disease
Interleukin-10 knockout mouse
Mouse mammary tumor virus
Online Access:https://doi.org/10.1186/s40168-023-01483-4

Internet

https://doi.org/10.1186/s40168-023-01483-4

Similar Items