CBD enhances the cognitive score of adolescent rats prenatally exposed to THC and fine-tunes relevant effectors of hippocampal plasticity

CBD enhances the cognitive score of adolescent rats prenatally exposed to THC and fine-tunes relevant effectors of hippocampal plasticity

Introduction: An altered neurodevelopmental trajectory associated with prenatal exposure to ∆-9-tetrahydrocannabinol (THC) leads to aberrant cognitive processing through a perturbation in the effectors of hippocampal plasticity in the juvenile offspring. As adolescence presents a unique window of op...

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Bibliographic Details
Main Authors: Valentina Castelli, Gianluca Lavanco, Cesare D’Amico, Salvatore Feo, Giuseppe Tringali, Martin Kuchar, Carla Cannizzaro, Anna Brancato
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Pharmacology
Subjects:
cannabidiol
prenatal THC exposure
adolescent offspring
spatial memory
hippocampal excitatory synapse
CB1R
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1237485/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1237485/full

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