Acute Surge of Atypical Memory and Plasma B-Cell Subsets Driven by an Extrafollicular Response in Severe COVID-19

Acute Surge of Atypical Memory and Plasma B-Cell Subsets Driven by an Extrafollicular Response in Severe COVID-19

BackgroundDespite the use of vaccines and therapeutics against the coronavirus disease 2019 (COVID-19) pandemic, this severe disease has been a critical burden on public health, whereas the pathogenic mechanism remains elusive. Recently, accumulating evidence underscores the potential role of the ab...

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Bibliographic Details
Main Authors: Taeseob Lee, Yuri Kim, Hyun Je Kim, Na-Young Ha, Siyoung Lee, BumSik Chin, Nam-Hyuk Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
B cells
extrafollicular response
COVID-19
antibody response
plasma cell
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.909218/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.909218/full

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