Porcine Circovirus Type 2 Activates CaMMKβ to Initiate Autophagy in PK-15 Cells by Increasing Cytosolic Calcium

Porcine Circovirus Type 2 Activates CaMMKβ to Initiate Autophagy in PK-15 Cells by Increasing Cytosolic Calcium

Porcine circovirus type 2 (PCV2) induces autophagy via the 5′ adenosine monophosphate-activated protein kinase (AMPK)/extracellular signal-regulated kinase (ERK)/tuberous sclerosis complex 2 (TSC2)/mammalian target of rapamycin (mTOR) pathway in pig kidney PK-15 cells. However, the underlying mechan...

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Bibliographic Details
Main Authors: Yuanxing Gu, Baozhu Qi, Yingshan Zhou, Xiaowu Jiang, Xian Zhang, Xiaoliang Li, Weihuan Fang
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Viruses
Subjects:
porcine circovirus 2
autophagy
Ca2+ signaling
pathogenesis
Online Access:http://www.mdpi.com/1999-4915/8/5/135

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http://www.mdpi.com/1999-4915/8/5/135

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