Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway

Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway

Summary: DNA interstrand crosslinks (ICLs) that are repaired in non-dividing cells must be recognized independently of replication-associated DNA unwinding. Using cell-free extracts from Xenopus eggs that support neither replication nor transcription, we establish that ICLs are recognized and proces...

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Bibliographic Details
Main Authors: Niyo Kato, Yoshitaka Kawasoe, Hannah Williams, Elena Coates, Upasana Roy, Yuqian Shi, Lorena S. Beese, Orlando D. Schärer, Hong Yan, Max E. Gottesman, Tatsuro S. Takahashi, Jean Gautier
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471731464X

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http://www.sciencedirect.com/science/article/pii/S221112471731464X

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