A proliferative subtype of colorectal liver metastases exhibits hypersensitivity to cytotoxic chemotherapy

A proliferative subtype of colorectal liver metastases exhibits hypersensitivity to cytotoxic chemotherapy

Abstract Personalized treatment approaches for patients with limited liver metastases from colorectal cancer are critically needed. By leveraging three large, independent cohorts of patients with colorectal liver metastases (n = 336), we found that a proliferative subtype associated with elevated CI...

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Bibliographic Details
Main Authors: Liam F. Spurr, Carlos A. Martinez, Rohan R. Katipally, Soumya C. Iyer, Sian A. Pugh, John A. Bridgewater, John N. Primrose, Enric Domingo, Timothy S. Maughan, Michael I. D’Angelica, Mark Talamonti, Mitchell C. Posner, Philip P. Connell, Ralph R. Weichselbaum, Sean P. Pitroda
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-022-00318-z

Internet

https://doi.org/10.1038/s41698-022-00318-z

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