Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?

Are the methylenetetrahydrofolate reductase 1298 and 677 gene polymorphisms related to optic glioma and hamartoma risk in neurofibromatosis type 1 patients?

The methylenetetrahydrofolate reductase (MTHFR) gene plays a key role in carcinogenesis through its effects on DNA synthesis and methylation and also has a significant role in the etiology of many disorders, such as diabetes, migraine, and cardiovascular disease. Neurofibromatoses (NF) are au...

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Bibliographic Details
Main Authors: Hikmet Gülşah Tanyıldız, Şule Yeşil, Ceyhun Bozkurt, Mehmet Onur Çandır, Sibel Akpınar-Tekgündüz, Şule Toprak, Deniz Yüksel, Gürses Şahin
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2016-04-01
Series:The Turkish Journal of Pediatrics
Subjects:
MTHFR gene polymorphism
neurofibromatosis type 1
Online Access:https://turkjpediatr.org/article/view/1088

Internet

https://turkjpediatr.org/article/view/1088

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