Signaling logic of activity-triggered dendritic protein synthesis: an mTOR gate but not a feedback switch.
Changes in synaptic efficacy are believed to form the cellular basis for memory. Protein synthesis in dendrites is needed to consolidate long-term synaptic changes. Many signals converge to regulate dendritic protein synthesis, including synaptic and cellular activity, and growth factors. The coordi...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-02-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2647780?pdf=render |