Signaling logic of activity-triggered dendritic protein synthesis: an mTOR gate but not a feedback switch.
Changes in synaptic efficacy are believed to form the cellular basis for memory. Protein synthesis in dendrites is needed to consolidate long-term synaptic changes. Many signals converge to regulate dendritic protein synthesis, including synaptic and cellular activity, and growth factors. The coordi...
Main Authors: | Pragati Jain, Upinder S Bhalla |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-02-01
|
Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2647780?pdf=render |
Similar Items
-
Dendrite pathology and neurodegeneration: focus on mTOR
by: Adriana Di Polo
Published: (2015-01-01) -
mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
by: Zhilin Zou, et al.
Published: (2020-03-01) -
Neuroligin 3 Regulates Dendritic Outgrowth by Modulating Akt/mTOR Signaling
by: Jing Xu, et al.
Published: (2019-11-01) -
Transcription control pathways decode patterned synaptic inputs into diverse mRNA expression profiles.
by: Pragati Jain, et al.
Published: (2014-01-01) -
mTOR Signalling, Nutrients and Disease
by: Goberdhan, D, et al.
Published: (2008)