Discovery of oxazole-dehydrozingerone based hybrid molecules as potential anti-tubercular agents and their docking for Mtb DNA gyrase
The oxazole-dehydrozingerone hybrid molecules (4a-j) and oxazole-dehydrozingerone-thiophene derivatives (6a-e) were synthesized via cyclisation, coupling and aldol condensation reactions. Final compounds were characterized by FTIR, 1H and 13C NMR spectroscopy. Synthesized compounds were screened aga...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-01-01
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Series: | Results in Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715622000935 |