Discovery of oxazole-dehydrozingerone based hybrid molecules as potential anti-tubercular agents and their docking for Mtb DNA gyrase

The oxazole-dehydrozingerone hybrid molecules (4a-j) and oxazole-dehydrozingerone-thiophene derivatives (6a-e) were synthesized via cyclisation, coupling and aldol condensation reactions. Final compounds were characterized by FTIR, 1H and 13C NMR spectroscopy. Synthesized compounds were screened aga...

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Bibliographic Details
Main Authors: Suraj R. Shinde, Shaukatali N. Inamdar, Vincent A. Obakachi, Mahadev Shinde, Afsana Kajee, Meenu Ghai, Rajshekhar Karpoormath
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715622000935