Upregulated Immunogenic Cell-Death-Associated Gene Signature Predicts Reduced Responsiveness to Immune-Checkpoint-Blockade Therapy and Poor Prognosis in High-Grade Gliomas

Upregulated Immunogenic Cell-Death-Associated Gene Signature Predicts Reduced Responsiveness to Immune-Checkpoint-Blockade Therapy and Poor Prognosis in High-Grade Gliomas

<b>Background:</b> Immunogenic cell death (ICD) has emerged as a potential mechanism mediating adaptive immune response and tumor immunity in anti-cancer treatment. However, the signature of ICD in high-grade gliomas (HGGs) remains largely unknown, and its relevance to immunotherapies is...

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Bibliographic Details
Main Authors: Xin Tang, Dongfang Guo, Xi Yang, Rui Chen, Qingming Jiang, Zhen Zeng, Yu Li, Zhenyu Li
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
glioma
immunogenic cell death
immune microenvironment
prognosis
immunotherapy
Online Access:https://www.mdpi.com/2073-4409/11/22/3655

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https://www.mdpi.com/2073-4409/11/22/3655

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