Genetic analyses reveal a role for vitamin D insufficiency in HCV-associated hepatocellular carcinoma development.

Vitamin D insufficiency has been associated with the occurrence of various types of cancer, but causal relationships remain elusive. We therefore aimed to determine the relationship between genetic determinants of vitamin D serum levels and the risk of developing hepatitis C virus (HCV)-related hepa...

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Bibliographic Details
Main Authors: Christian M Lange, Daiki Miki, Hidenori Ochi, Hans-Dieter Nischalke, Jörg Bojunga, Stéphanie Bibert, Kenichi Morikawa, Jérôme Gouttenoire, Andreas Cerny, Jean-François Dufour, Meri Gorgievski-Hrisoho, Markus H Heim, Raffaele Malinverni, Beat Müllhaupt, Francesco Negro, David Semela, Zoltan Kutalik, Tobias Müller, Ulrich Spengler, Thomas Berg, Kazuaki Chayama, Darius Moradpour, Pierre-Yves Bochud, Hiroshima Liver Study Group, Swiss Hepatitis C Cohort Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3667029?pdf=render