Integrated Deadenylase Genetic Association Network and Transcriptome Analysis in Thoracic Carcinomas

Integrated Deadenylase Genetic Association Network and Transcriptome Analysis in Thoracic Carcinomas

The poly(A) tail at the 3′ end of mRNAs determines their stability, translational efficiency, and fate. The shortening of the poly(A) tail, and its efficient removal, triggers the degradation of mRNAs, thus, regulating gene expression. The process is catalyzed by a family of enzymes, known as deaden...

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Bibliographic Details
Main Authors: Athanasios Kyritsis, Eirini Papanastasi, Ioanna Kokkori, Panagiotis Maragozidis, Demetra S. M. Chatzileontiadou, Paschalina Pallaki, Maria Labrou, Sotirios G. Zarogiannis, George P. Chrousos, Dimitrios Vlachakis, Konstantinos I. Gourgoulianis, Nikolaos A. A. Balatsos
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
deadenylases
lung cancer
association network
transcriptomics
mRNA degradation
Online Access:https://www.mdpi.com/1420-3049/27/10/3102

Internet

https://www.mdpi.com/1420-3049/27/10/3102

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