Read Count Patterns and Detection of Cancerous Copy Number Alterations in Plasma Cell-Free DNA Whole Exome Sequencing Data for Advanced Non-Small Cell Lung Cancer

Read Count Patterns and Detection of Cancerous Copy Number Alterations in Plasma Cell-Free DNA Whole Exome Sequencing Data for Advanced Non-Small Cell Lung Cancer

Plasma cell-free DNA (cfDNA) sequencing data have been widely studied for early diagnosis and treatment response or recurrence monitoring of cancers because of the non-invasive benefits. In cancer studies, whole exome sequencing (WES) is mostly used for discovering single nucleotide variants (SNVs),...

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Bibliographic Details
Main Authors: Ho Jang, Chang-Min Choi, Seung-Hyeun Lee, Sungyong Lee, Mi-Kyung Jeong
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
plasma cell-free DNA
whole exome sequencing
copy number alteration detection
non-small cell lung cancer
Online Access:https://www.mdpi.com/1422-0067/23/21/12932

Internet

https://www.mdpi.com/1422-0067/23/21/12932

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