Does hyperglycemia affect arginine metabolites in critically ill patients? A prospective cohort and in vitro study

Does hyperglycemia affect arginine metabolites in critically ill patients? A prospective cohort and in vitro study

Abstract Background Changes in the arginine metabolites asymmetric dimethyl-L-arginine (ADMA) and L-homoarginine and acute blood glucose concentrations have been shown to cause endothelial dysfunction and be independently associated with mortality in Intensive Care Unit (ICU) patients. The aim of th...

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Bibliographic Details
Main Authors: Tien F. Lee, Sara Tommasi, Andrew Bersten, Leonie K. Heilbronn, Salvatore Sotgia, Angelo Zinellu, Ciriaco Carru, Arduino A. Mangoni, Morton G. Burt
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Stress hyperglycemia ratio
Asymmetric dimethyl-l-arginine
l-homoarginine
Endothelial function
Critical illness
Dimethylarginine-dimethylaminohydrolase 1
Online Access:https://doi.org/10.1186/s13098-023-01035-8

Internet

https://doi.org/10.1186/s13098-023-01035-8

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