Preclinical evaluation of Insulin-like growth factor receptor 1 (IGF1R) and Insulin Receptor (IR) as a therapeutic targets in triple negative breast cancer

Preclinical evaluation of Insulin-like growth factor receptor 1 (IGF1R) and Insulin Receptor (IR) as a therapeutic targets in triple negative breast cancer

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Triple Negative Breast Cancer (TNBC), a subtype of breast cancer, has fewer successful therapeutic therapies than other types of breast cancer. Insulin-like growth factor receptor 1 (IGF1R) and the Insulin receptor (IR) are associated with poor outcomes in TNBC. Targeting IGF1R has failed clinically...

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Bibliographic Details
Main Authors: Sandra Roche, Patricia Gaule, Deirdre Winrow, Nupur Mukherjee, Fiona O’Neill, Neil T. Conlon, Justine Meiller, Denis M. Collins, Alexandra Canonici, Mohammed Ibrahim Fawsi, Alejandra Estepa-Fernández, Stephen F. Madden, John Crown, Norma O’Donovan, Alex J. Eustace
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016661/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10016661/?tool=EBI

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