1,4-Dihydropyridine as a Promising Scaffold for Novel Antimicrobials Against Helicobacter pylori

1,4-Dihydropyridine as a Promising Scaffold for Novel Antimicrobials Against Helicobacter pylori

The increasing occurrence of multidrug-resistant strains of the gastric carcinogenic bacterium Helicobacter pylori threatens the efficacy of current eradication therapies. In a previous work, we found that several 1,4-dihydropyridine (DHP)-based antihypertensive drugs exhibited strong bactericidal a...

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Bibliographic Details
Main Authors: Andrés González, Javier Casado, Miyase Gözde Gündüz, Brisa Santos, Adrián Velázquez-Campoy, Cristina Sarasa-Buisan, María F. Fillat, Milagrosa Montes, Elena Piazuelo, Ángel Lanas
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Microbiology
Subjects:
Helicobacter pylori
HsrA
hexahydroquinoline
novel antimicrobial drugs
antibiotic resistance
dihydropyridine
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.874709/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.874709/full

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