Endotoxin- and ATP-neutralizing activity of alkaline phosphatase as a strategy to limit neuroinflammation
<p>Abstract</p> <p>Background</p> <p>Alkaline phosphatase (AP) is a ubiquitously expressed enzyme which can neutralize endotoxin as well as adenosine triphosphate (ATP), an endogenous danger signal released during brain injury. In this study we assessed a potential ther...
Main Authors: | Huizinga Ruth, Kreft Karim L, Onderwater Sabina, Boonstra Joke G, Brands Ruud, Hintzen Rogier Q, Laman Jon D |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-12-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://www.jneuroinflammation.com/content/9/1/266 |
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