H-Ras induces exuberant de novo dendritic protrusion growth in mature neurons regardless of cell type

H-Ras induces exuberant de novo dendritic protrusion growth in mature neurons regardless of cell type

Summary: Dendritic protrusions, mainly spines and filopodia, correlate with excitatory synapses in pyramidal neurons (PyNs), but this relationship may not apply universally. We found that ectopic H-Ras expression increased protrusions across various cortical cell types, including layer 2/3 PyNs, par...

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Bibliographic Details
Main Authors: Sarah Krüssel, Ishana Deb, Seungkyu Son, Gabrielle Ewall, Minhyeok Chang, Hey-Kyoung Lee, Won Do Heo, Hyung-Bae Kwon
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:iScience
Subjects:
Molecular biology
Neuroscience
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224017607

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224017607

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