Widespread ribosome stalling in a genome-reduced bacterium and the need for translational quality control

Widespread ribosome stalling in a genome-reduced bacterium and the need for translational quality control

Summary: Trans-translation is a ubiquitous bacterial mechanism of ribosome rescue mediated by a transfer-messenger RNA (tmRNA) that adds a degradation tag to the truncated nascent polypeptide. Here, we characterize this quality control system in a genome-reduced bacterium, Mycoplasma pneumoniae (MPN...

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Bibliographic Details
Main Authors: Raul Burgos, Marc Weber, Carolina Gallo, Maria Lluch-Senar, Luis Serrano
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
biological sciences
molecular biology
molecular mechanism of gene regulation
cell biology
transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221009536

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http://www.sciencedirect.com/science/article/pii/S2589004221009536

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