Bacillus thuringiensis toxins divert progenitor cells toward enteroendocrine fate by decreasing cell adhesion with intestinal stem cells in Drosophila

Bacillus thuringiensis toxins divert progenitor cells toward enteroendocrine fate by decreasing cell adhesion with intestinal stem cells in Drosophila

Bacillus thuringiensis subsp. kurstaki (Btk) is a strong pathogen toward lepidopteran larvae thanks to specific Cry toxins causing leaky gut phenotypes. Hence, Btk and its toxins are used worldwide as microbial insecticide and in genetically modified crops, respectively, to fight crop pests. However...

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Bibliographic Details
Main Authors: Rouba Jneid, Rihab Loudhaief, Nathalie Zucchini-Pascal, Marie-Paule Nawrot-Esposito, Arnaud Fichant, Raphael Rousset, Mathilde Bonis, Dani Osman, Armel Gallet
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-02-01
Series:eLife
Subjects:
bacillus thurigiensis
Cry1A toxins
intestinal stem cells
Drosophila melanogaster
enteroendocrine cells
E-Cadherins
Online Access:https://elifesciences.org/articles/80179

Internet

https://elifesciences.org/articles/80179

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