Chronic Chemogenetic Activation of the Superior Colliculus in Glaucomatous Mice: Local and Retrograde Molecular Signature

Chronic Chemogenetic Activation of the Superior Colliculus in Glaucomatous Mice: Local and Retrograde Molecular Signature

One important facet of glaucoma pathophysiology is axonal damage, which ultimately disrupts the connection between the retina and its postsynaptic brain targets. The concurrent loss of retrograde support interferes with the functionality and survival of the retinal ganglion cells (RGCs). Previous re...

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Bibliographic Details
Main Authors: Marie Claes, Emiel Geeraerts, Stéphane Plaisance, Stephanie Mentens, Chris Van den Haute, Lies De Groef, Lut Arckens, Lieve Moons
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
chemogenetics
DREADDs
glaucoma
retinal ganglion cells
superior colliculus
postsynaptic target area
Online Access:https://www.mdpi.com/2073-4409/11/11/1784

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https://www.mdpi.com/2073-4409/11/11/1784

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