Analysis of commonly expressed genes between first trimester fetal heart and placenta cell types in the context of congenital heart disease

Abstract Congenital heart disease (CHD) is often associated with fetal growth abnormalities. During the first trimester of pregnancy, the heart and placenta develop concurrently, and share key developmental pathways. It is hypothesized that defective morphogenesis of either organ is synergistically...

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Bibliographic Details
Main Authors: Rebecca L. Wilson, Victor Yuan, Jennifer A. Courtney, Alyssa Tipler, James F. Cnota, Helen N. Jones
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-14955-8