Generating Patient-Derived Gliomas within Cerebral Organoids

Summary: Glioblastoma (GBM) remains a devastating disease with a median survival of less than two years. Current preclinical models are unable to accurately reflect the complexity of human GBM. We recently established a cerebral organoid glioma (GLICO) model to study the invasion and biology of pati...

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Bibliographic Details
Main Authors: Amanda Linkous, Howard A. Fine
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:STAR Protocols
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166719300085