Prenatal Diagnosis of Fetuses With Increased Nuchal Translucency by Genome Sequencing Analysis

Prenatal Diagnosis of Fetuses With Increased Nuchal Translucency by Genome Sequencing Analysis

Background: Increased nuchal translucency (NT) is an important biomarker associated with increased risk of fetal structural anomalies. It is known to be contributed by a wide range of genetic etiologies from single-nucleotide variants to those affecting millions of base pairs. Currently, prenatal di...

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Bibliographic Details
Main Authors: Kwong Wai Choy, Huilin Wang, Mengmeng Shi, Jingsi Chen, Zhenjun Yang, Rui Zhang, Huanchen Yan, Yanfang Wang, Shaoyun Chen, Matthew Hoi Kin Chau, Ye Cao, Olivia Y.M. Chan, Yvonne K. Kwok, Yuanfang Zhu, Min Chen, Tak Yeung Leung, Zirui Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Genetics
Subjects:
increased nuchal translucency
genome sequencing
prenatal diagnosis
genomic variants
structural rearrangement
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00761/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00761/full

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