Minimally invasive sampling to identify leprosy patients with a high bacterial burden in the Union of the Comoros

The World Health Organization (WHO) endorsed diagnosis of leprosy (also known as Hansen’s disease) entirely based on clinical cardinal signs, without microbiological confirmation, which may lead to late or misdiagnosis. The use of slit skin smears is variable, but lacks sensitivity. In 2017–2018 dur...

Full description

Bibliographic Details
Main Authors: Sofie Marijke Braet, Anouk van Hooij, Epco Hasker, Erik Fransen, Abdou Wirdane, Abdallah Baco, Saverio Grillone, Nimer Ortuno-Gutierrez, Younoussa Assoumani, Aboubacar Mzembaba, Paul Corstjens, Leen Rigouts, Annemieke Geluk, Bouke Catherine de Jong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580230/?tool=EBI