Thymic function recovery after unrelated donor cord blood or T-cell depleted HLA-haploidentical stem cell transplantation correlates with leukemia relapse

Thymic function recovery after unrelated donor cord blood or T-cell depleted HLA-haploidentical stem cell transplantation correlates with leukemia relapse

Use of alternative donors/sources of hematopoietic stem cells (HSC), such as cord blood (CB) or HLA-haploidentical (Haplo) related donors, is associated with a significant delay in immune reconstitution after transplantation. Long-term T-cell immune reconstitution largely relies on the generation of...

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Bibliographic Details
Main Authors: Emmanuel eClave, Daniela eLisini, Corinne eDouay, Giovana eGiorgiani, Marc eBUSSON, Marco eZecca, Francesca eMoretta, Gloria eAcquafredda, Letizia Pomponia Brescia, Franco eLocatelli, Antoine eToubert
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Immunology
Subjects:
Leukemia
T cells
relapse
HSCT
Thymic function
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00054/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00054/full

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