Novel 1,2,3-Triazole-Based Benzothiazole Derivatives: Efficient Synthesis, DFT, Molecular Docking, and ADMET Studies

A new series of 1,2,3-triazole derivatives <b>5a</b>–<b>f</b> based on benzothiazole were synthesized by the 1,3-dipolar cycloaddition reaction of S-propargyl mercaptobenzothiazole and α-halo ester/amide in moderate to good yields (47–75%). The structure of all products was c...

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Bibliographic Details
Main Authors: Zohreh Mirjafary, Mahdieh Mohammad Karbasi, Parsa Hesamzadeh, Hamid Reza Shaker, Asghar Amiri, Hamid Saeidian
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/23/8555