Origin of exon skipping-rich transcriptomes in animals driven by evolution of gene architecture

Origin of exon skipping-rich transcriptomes in animals driven by evolution of gene architecture

Abstract Background Alternative splicing, particularly through intron retention and exon skipping, is a major layer of pre-translational regulation in eukaryotes. While intron retention is believed to be the most prevalent mode across non-animal eukaryotes, animals have unusually high rates of exon...

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Bibliographic Details
Main Authors: Xavier Grau-Bové, Iñaki Ruiz-Trillo, Manuel Irimia
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Genome Biology
Subjects:
Alternative splicing
Exon skipping
Intron retention
Ancestral reconstruction
Gene architecture
Evolution of transcriptome regulation
Online Access:http://link.springer.com/article/10.1186/s13059-018-1499-9

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http://link.springer.com/article/10.1186/s13059-018-1499-9

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