The PPAR-gamma agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function

<p>Abstract</p> <p>Background</p> <p>Inflammation is known to play a pivotal role in mediating neuronal damage and axonal injury in a variety of neurodegenerative disorders. Among the range of inflammatory mediators, nitric oxide and hydrogen peroxide are potent neuroto...

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Bibliographic Details
Main Authors: Gray Elizabeth, Ginty Mark, Kemp Kevin, Scolding Neil, Wilkins Alastair
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://www.jneuroinflammation.com/content/9/1/63