The PPAR-gamma agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function
<p>Abstract</p> <p>Background</p> <p>Inflammation is known to play a pivotal role in mediating neuronal damage and axonal injury in a variety of neurodegenerative disorders. Among the range of inflammatory mediators, nitric oxide and hydrogen peroxide are potent neuroto...
Main Authors: | Gray Elizabeth, Ginty Mark, Kemp Kevin, Scolding Neil, Wilkins Alastair |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-04-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://www.jneuroinflammation.com/content/9/1/63 |
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