Prediction of the Molecular Mechanisms Underlying Erlong Zuoci Treatment of Age-Related Hearing Loss via Network Pharmacology-Based Analyses Combined with Experimental Validation

Prediction of the Molecular Mechanisms Underlying Erlong Zuoci Treatment of Age-Related Hearing Loss via Network Pharmacology-Based Analyses Combined with Experimental Validation

Background: The traditional Chinese medicine formula ErLong ZuoCi (ELZC) has been extensively used to treat age-related hearing loss (ARHL) in clinical practice in China for centuries. However, the underlying molecular mechanisms are still poorly understood.Objective: Combine network pharmacology wi...

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Bibliographic Details
Main Authors: Qing Liu, Ning Li, Yifang Yang, Xirui Yan, Yang Dong, Yinting Peng, Jianrong Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
erlong zuoci
age-related hearing loss
network pharmacology
experimental validation
cellular senescence
inflammatory response
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.719267/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.719267/full

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