Characterization of the circulating transcriptome expression profile and identification of novel miRNA biomarkers in hypertrophic cardiomyopathy

Characterization of the circulating transcriptome expression profile and identification of novel miRNA biomarkers in hypertrophic cardiomyopathy

Abstract Background Hypertrophic cardiomyopathy (HCM), one of the most common genetic cardiovascular diseases, but cannot be explained by single genetic factors. Circulating microRNAs (miRNAs) are stable and highly conserved. Inflammation and immune response participate in HCM pathophysiology, but w...

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Bibliographic Details
Main Authors: Lanyan Guo, Yue Cai, Bo Wang, Fuyang Zhang, Hang Zhao, Liwen Liu, Ling Tao
Format: Article
Language:English
Published: BMC 2023-06-01
Series:European Journal of Medical Research
Subjects:
Hypertrophic cardiomyopathy
miRNAs
Weighted correlation network analysis
Gene set enrichment analysis
Competing endogenous RNA network
Online Access:https://doi.org/10.1186/s40001-023-01159-7

Internet

https://doi.org/10.1186/s40001-023-01159-7

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