Degradation of methylation signals in cryopreserved DNA
Abstract Background Blood-based DNA methylation has shown great promise as a biomarker in a wide variety of diseases. Studies of DNA methylation in blood often utilize samples which have been cryopreserved for years or even decades. Therefore, changes in DNA methylation associated with long-term cry...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-09-01
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Series: | Clinical Epigenetics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13148-023-01565-y |