Simvastatin Sodium Salt and Fluvastatin Interact with Human Gap Junction Gamma-3 Protein.

Simvastatin Sodium Salt and Fluvastatin Interact with Human Gap Junction Gamma-3 Protein.

Finding pleiomorphic targets for drugs allows new indications or warnings for treatment to be identified. As test of concept, we applied a new chemical genomics approach to uncover additional targets for the widely prescribed lipid-lowering pro-drug simvastatin. We used mRNA extracted from internal...

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Bibliographic Details
Main Authors: Andrew Marsh, Katherine Casey-Green, Fay Probert, David Withall, Daniel A Mitchell, Suzanne J Dilly, Sean James, Wade Dimitri, Sweta R Ladwa, Paul C Taylor, Donald R J Singer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4749215?pdf=render

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http://europepmc.org/articles/PMC4749215?pdf=render

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