Neural networks for self-adjusting mutation rate estimation when the recombination rate is unknown.

Estimating the mutation rate, or equivalently effective population size, is a common task in population genetics. If recombination is low or high, optimal linear estimation methods are known and well understood. For intermediate recombination rates, the calculation of optimal estimators is more chal...

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Bibliographic Details
Main Authors: Klara Elisabeth Burger, Peter Pfaffelhuber, Franz Baumdicker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010407