Left ventricular hypertrophy in experimental chronic kidney disease is associated with reduced expression of cardiac Kruppel-like factor 15

Left ventricular hypertrophy in experimental chronic kidney disease is associated with reduced expression of cardiac Kruppel-like factor 15

Abstract Background Left ventricular hypertrophy (LVH) increases the risk of death in chronic kidney disease (CKD). The transcription factor Kruppel-like factor 15 (KLF15) is expressed in the heart and regulates cardiac remodelling through inhibition of hypertrophy and fibrosis. It is unknown if KLF...

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Bibliographic Details
Main Authors: Sheila K. Patel, Elena Velkoska, Daniel Gayed, Jay Ramchand, Jessica Lesmana, Louise M. Burrell
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Nephrology
Subjects:
KLF15
Kruppel-like factor 15
Renin angiotensin system
Left ventricular hypertrophy
ACE inhibition
Subtotal nephrectomy
Online Access:http://link.springer.com/article/10.1186/s12882-018-0955-9

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http://link.springer.com/article/10.1186/s12882-018-0955-9

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