Sensitive assessment of the virologic outcomes of stopping and restarting non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy.

Sensitive assessment of the virologic outcomes of stopping and restarting non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy.

Non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant mutants have been shown to emerge after interruption of suppressive NNRTI-based antiretroviral therapy (ART) using routine testing. The aim of this study was to quantify the risk of resistance by sensitive testing and correlate the det...

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Bibliographic Details
Main Authors: Anna Maria Geretti, Zoe Fox, Jeffrey A Johnson, Clare Booth, Jonathan Lipscomb, Lieven J Stuyver, Gilda Tachedjian, John Baxter, Giota Touloumi, Clara Lehmann, Andrew Owen, Andrew Phillips, INSIGHT Strategies for Management of Antiretroviral Therapy (SMART) Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3715458?pdf=render

Internet

http://europepmc.org/articles/PMC3715458?pdf=render

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