Comparison of the efficacy and safety of tacrolimus monotherapy and cyclophosphamide combined with glucocorticoid in the treatment of adult primary membranous nephropathy: protocol of a multicenter, randomized, controlled, open study

Comparison of the efficacy and safety of tacrolimus monotherapy and cyclophosphamide combined with glucocorticoid in the treatment of adult primary membranous nephropathy: protocol of a multicenter, randomized, controlled, open study

Abstract Background Idiopathic membranous nephropathy (IMN) remains the leading cause of adult nephrotic syndrome. Immunosuppressive therapy with cyclophosphamide (CTX) is often successful in reducing proteinuria, but its use is associated with severe side effects. Tacrolimus (TAC) is effective in a...

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Bibliographic Details
Main Authors: Shasha Chen, Song Ren, Amanda Y. Wang, Hieu Tran, Zheng Li, Xiaoyun Cheng, Manli Liu, Guisen Li, Li Wang, Daqing Hong
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Trials
Subjects:
Tacrolimus, Cyclophosphamide, Glucocorticoid, Membranous nephropathy, Randomized controlled trial
Online Access:http://link.springer.com/article/10.1186/s13063-020-4144-3

Internet

http://link.springer.com/article/10.1186/s13063-020-4144-3

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