Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-κB pathways in diabetic neuropathy

Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-κB pathways in diabetic neuropathy

The Nuclear factor-2 erythroid related factor-2 (Nrf2) is a redox regulated transcription factor involved in the regulation of antioxidant defence systems. It drives the production of endogenous antioxidant defences and detoxifying enzymes. Nuclear factor-kappa light chain enhancer of B cells (NF-κB...

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Bibliographic Details
Main Authors: Veera Ganesh Yerra, Geeta Negi, Shyam S Sharma, Ashutosh Kumar
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Nrf2
NF-κB
Diabetic neuropathy
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231713000578

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http://www.sciencedirect.com/science/article/pii/S2213231713000578

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