Milk oligosaccharide-driven persistence of Bifidobacterium pseudocatenulatum modulates local and systemic microbial metabolites upon synbiotic treatment in conventionally colonized mice

Abstract Background Bifidobacteria represent an important gut commensal in humans, particularly during initial microbiome assembly in the first year of life. Enrichment of Bifidobacterium is mediated though the utilization of human milk oligosaccharides (HMOs), as several human-adapted species have...

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Bibliographic Details
Main Authors: Jules A. Larke, Britta E. Heiss, Amy M. Ehrlich, Diana H. Taft, Helen E. Raybould, David A. Mills, Carolyn M. Slupsky
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Microbiome
Subjects:
Online Access:https://doi.org/10.1186/s40168-023-01624-9